How Various Laboratories Such As Scientific Research And Hospitals Choose The Type of Centrifuge:

How various laboratories such as scientific research and hospitals choose the type of centrifuge:

1. When solid-phase material consists of crystalline products, low damage to the crystals during separation is required.

Selection of centrifuge type should consider factors such as the size and concentration of solid particles in the suspension (or emulsion), density difference between solid and liquid phases (or between two liquids), liquid viscosity, and characteristics of filter residue (or sediment).

2. When particle diameters range from 1 micron to 50 microns, low-speed centrifuges can be used.

Typical speeds range from approximately 4000 to 7000 rpm, providing relative centrifugal forces of about 2000g to 9420g. Generally, tabletop low-speed centrifuges or floor-standing models with large capacity are employed.

3. For substances like viruses within animal or plant tissues, with diameters around 0.1 micron to 1 micron, high-speed refrigerated centrifuges are recommended.

Operating speeds range from 10,000 to 20,000 rpm, producing centrifugal forces of about 10,000g to 100,000g.

4. Components such as proteins, DNA, RNA, with diameters ranging from 0.002 micron to 0.1 micron, require ultracentrifuges.

Speeds exceed 40,000 rpm, generating centrifugal forces of 100,000g to over 400,000g.

5. When materials contain flammable or explosive substances like benzene, toluene, petroleum ether, cyclohexane, dichloroethane, carbon tetrachloride, methanol, ethanol, diethyl ether, methyl ethyl ether, acetone, cyclohexanone, ethylene glycol ether, ethylene glycol butyl ether, formaldehyde, acetaldehyde, pyridine, etc., explosion-proof centrifuges should be chosen.

6. For separating organic active substances such as enzymes while maintaining constant temperature during the process, refrigerated centrifuges are selected.